Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14b02369b953bf4ebd31190c8cb63473 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-16 |
filingDate |
1988-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ab06759c62d9b2dd933cd550859ce12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c2c209420e4fad000e1eac5c1861bda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_006980aeeac6bb3a2adc91d664336e77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee727517e86a41e8550b8a01b821e983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c6271aa7a69f61a193ad6881902d28 |
publicationDate |
1989-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H01199979-A |
titleOfInvention |
Novel quinolinecarboxylic acid derivative and antibacterial agent comprising said compound as active ingredient |
abstract |
NEW MATERIAL:A compound shown by formula I (Z is group shown by formula II or formula III; R<1> is H or lower alkyl; R<3> is H, OH or lower alkyl; R<3> is H, OH or amino). EXAMPLE:9,1-Epoxymethano-7-fluoro-8-(4-methyl-1-piperazinyl)-5--oxo-5H -thiazolo [3,2-a]quinoline-4-carboxylic acid. USE:Having strongly antibacterial activity against Staphylococcus aureus having methicillin resistance. PREPARATION:(B) A compound shown by formula II is reacted with (C) a cyclic amine (ZH) or an acid addition salt thereof in (A) a polar organic solvent such as dimethyl sulfoxide in the presence of an acid scavenger. |
priorityDate |
1987-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |