| abstract |
NEW MATERIAL: The compound of formula I [R 1 is H, 1-20C alkyl, 3-20C alkenyl or (substituted) 6-20C aryl; R 2 is 1-6C alkyl, (substituted) 6-12C aryl, (substituted) 7-13C aroyl or the like; A is formula II, III or the like; R 3 is H, hydroxymethyl, formyl or the like; X is oxygen, imino or N-1-8C alkylimino; (m) is 0 to 5; (n) is 0 or 1]. n EXAMPLE: N-[N-(4-phenylbutylyl)-(2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2- carbonyl]-S-prolinol. n USE: Prolilendopeptidase inhibitors. Being suitable for neurotropic drugs or antipsychotic drugs. n PROCESS: The compound of formula I is obtained by allowing the compound of formula IV (Y is OH, 1-10C alkoxy, 6-12C aryloxy or the like) to react with the compound of formula V. n COPYRIGHT: (C)1989,JPO |