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filingDate 1988-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1989-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H01163180-A
titleOfInvention Process for antifungal fermentation product
abstract NEW MATERIAL: The antibiotic compound represented by formula and named as 1-[(4R,5R)-4,5-dihydroxy-N 2 -(10,12-dimethyl-1-oxotetradecil)-L- ornithine]-5-(treo-3-hydroxy-1-glutamin)-ethynocandin B. n USE: Having very high activity against human fungal infection substantially with no toxicity and no undesirable effect. n PROCESS: The strain ATCC20868 of fungus has not been fixed in a nutritional medium is aerobically cultured until a substantial quantity of antifungal activity is generated preferably at about 20 to 40°C for about 3 to 30 days. Then the compound of formula is obtained by recovering the active component from the medium preferably by an alcohol, condensing thereof, extracting or distributing thereof in a specific solvent such as an oxygenated organic solvent not be mixed with water, again condensing and separating by a chromatography at least once. n COPYRIGHT: (C)1989,JPO
priorityDate 1987-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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