http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01156977-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D461-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 1988-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b214178afa2372f0fe623f0df166bd4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e2d1c4136631fafca72b2b3e4a3e604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0e50c6c44d90ca1a71e830c98c16aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54966abe0017ec099eb936e08707c1f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3b1631dfe304ba656f8d4a31379ed6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee22ae49d54d03e776a84fea51064fd |
| publicationDate | 1989-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H01156977-A |
| titleOfInvention | Vincaminic acid derivative |
| abstract | NEW MATERIAL:A vincaminic acid derivative expressed by formula I (R 1 is H, alkyl or alkoxy; R 2 is H, alkyl, halogenated alkyl, cycloalkyl, alkoxycarbonylalkyl, alkenyl, phenyl, alkoxy-substituted phenyl or thienyl; A is hydroxyl; B is H or, together with B, forms valent bond) and acid addition salt thereof. n EXAMPLE: Methyl 10-acetylapovincaminate. n USE: A remedy for cerebral angiopathy capable or remarkably improving effects on cerebral angiopathy by introducing an acyl or formyl group into the benzene ring of an eburnamenine skeleton. n PREPARATION: For example, a vincaminic acid derivative expressed by formula II is subjected to the Friedel-Crafts reaction using an acylating agent having a group of R 2 CO-(dichloromethyl methyl ether when R 2 is H) to afford the aimed compound expressed by formula I. n COPYRIGHT: (C)1989,JPO&Japio |
| priorityDate | 1987-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.