| abstract |
NEW MATERIAL:The compound of formula I [R 1 is H, halogen, alkyl, alkoxy, alkoxycarbonyl or trifluoromethyl; X is -S- or -SO-; R 2 is alkyl; R 3 is H, alkyl, (substituted) aralkyl or (substituted) heteroaralkyl; R 4 is H or alkyl] or its addition salt. n EXAMPLE: 2-(5-Benzyl-4-methoxy-6-methyl-2-pyrimidinyl)methylthio-1 Hbenzimidazole. n USE: An antiulcer agent. It has gastric inhibitory action. n PREPARATION: A compound of formula I wherein the group X is -SO- can be produced by reacting a compound of formula II (Hal is halogen) with a compound of formula R 2 OH. n COPYRIGHT: (C)1989,JPO&Japio |