abstract |
PURPOSE: To obtain contraceptives by using both estrogen and progestin and administering them so that a short period showing comparatively dominant estrogen activities and a short time showing comparatively dominant progestin activities may be alternative. n CONSTITUTION: This hormone preparation comprises a mixture of estrogen and progestin selected from the mixture having comparatively dominant estrogen activities (e.g. 17α-ethynylestradiol) and the mixture having comparatively dominant progestin activities (e.g. norethindrone). The dose units of 20-35 are successively administered every day. The amount of the estrogen in the dose unit is 0.020-0.050mg and that of the progestin is 0.00-1.00mg. The hormone preparation is medicated in a form of oral, subglossal, dermal, intracavital, nosal, parenteral or oral cavity administration. n COPYRIGHT: (C)1989,JPO |