| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9647161fb602828d512f4438d0a865e0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-225 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-225
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-232
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-04 |
| filingDate |
1988-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d84fd7c76c54528ee554011e06eabab |
| publicationDate |
1989-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H01125339-A |
| titleOfInvention |
Production of 1,4-bis(2,2,2-trifluoroethoxy)benzene |
| abstract |
PURPOSE: To obtain the compd. which allows the inexpensive production of an antiarrhythmic agent (flecainide and its salt) by the operation easier than by the known methods at a relatively high yield by bringing a hydroquinone or 1,4-bromobenzene into reaction with a specific alkylating agent. n CONSTITUTION: The objective compd. of formula III which allows the advantageous production of the compd. of formula II and its salt useful as the medicine described above from a relatively inexpensive starting material is obtd. by bringing the compd. of the formula I (X is the same, OH, Br) into reaction with the alkylating agent of formula CF 3 CH 2 O-A (A is SO 2 CF 3 when X is OH and an alkaline metal when X is Br). The objective compd. of formula III is obtainable at a good yield particularly if the compd. of the formula I in which X is Br and the alkylating agent in which A is the alkaline metal are brought into reaction in a polar solvent to the intensity of contg. 2,2,2- trifluoroethanol preferably in the presence of cuprous ions or cupric ions. n COPYRIGHT: (C)1989,JPO |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007119424-A |
| priorityDate |
1979-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |