| abstract |
PURPOSE: To obtain the subject aqueous composition which contains concholytic acid and a silanol (or its derivative), improves the tissues of the wall of lymphatic vessels, increase the durability of corresponding lymph capillaries and recover the viscosity of lymph liquid to a suitable level. n CONSTITUTION: This aqueous composition contains 0.05-0.5wt.% of concoritte acid (an extract from shell of molluscs, particularly from the pearl layer is suitable) and a silanol or its derivative, respectively. As a silanol, 0.05-0.5wt.% of proteosilane of formula I (R is a hydrocarbon group, particularly a 1-8C alkyl; n is 1-3; at least one of H may be replaced with a 1-18C alkyl), formula II [R'COOH is an acid; X=4-n; a part of H in Si(OH) 4-n may be replaced with a hydrocarbon], formula III (n is 0-20, particularly 0-4). In addition, a proteosilane of formula IV (R is an organic group, particularly 1-18C alkenyl; n is 1-3; R' is a group active to skin; R" is protide group) is added to the composition in an amount of 0.05-0.5wt.%. n COPYRIGHT: (C)1989,JPO |