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filingDate 1987-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_250a9c2452a7ba6ed69834cd7eb96025
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publicationDate 1989-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H01113399-A
titleOfInvention Fluoropentofuranosides
abstract NEW MATERIAL:A compound expressed by the formula [R 1 are residue of nucleic acid bases which may have a protecting group, halogen or formula OX (X is H, protecting group or alkyl); R 2 is protecting group of H or hydroxyl group]. n EXAMPLE: 2',3'-Deoxy-2'-fluorouridine. n USE: An antiulcer agent or antiviral agent. n PREPARATION: For example, 5'-O-tert.-butyldimethylsilyl-2'-deoxy-2'-fluorouridine dissolved in methylene chloride, etc., is reacted with 4-dimethylaminopyridine and phenylchlorothionocarbonate added to the above-mentioned solution to afford 5'-O-tert.-butyldimethylsilyl-2',3'-dideoxy-2'-fluorouridine, which is then reacted with tetrabutylammonium added to the above-mentioned fluorouridine derivative and the resultant reaction product is purified with a column chromatography to provide the compound expressed by the formula. n COPYRIGHT: (C)1989,JPO&Japio
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priorityDate 1987-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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