abstract |
1,2-di-O-galloyl-4,6-O- (S) -hexahydroxydiphenoyl-β-D-glucose (abbreviated below), abundant in Kenyan purple tea (scientific name: Camellia sinensis, variety TRFK306) "GHG") and new circadian rhythm regulators that can be used for a wide range of uses as medicines, foods and drinks, and cosmetics. The circadian rhythm regulating agent of the present invention is characterized in that it contains GHG as an active ingredient of the Bmal1 gene expression promoting action. Moreover, the circadian rhythm regulator of this invention is characterized by containing the GHG containing extract derived from Kenyan purple tea as an active ingredient of a Bmal1 gene expression promotion effect | action. |