http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5456144-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-5456144-B1 |
| titleOfInvention | Angiotensin converting enzyme inhibitory dipeptide |
| abstract | Kind Code: A1 Five useful dipeptides having an activity of inhibiting angiotensin converting enzyme and exhibiting a blood pressure lowering action and peptide compositions containing the same are provided. SOLUTION: Fish-like protein is extracted with hot water, water-insoluble protein remaining in the hot-water extraction section is pulverized, and the obtained pulverized product is dispersed in moisture to obtain the water-insoluble protein particles. Reacting the protease at a temperature of 40-60 ° C. under optimal conditions of pH 5.0-7.0, thereby carrying out the enzymatic hydrolysis of the water-insoluble protein, after which the enzymatic reaction is stopped and obtained Water-insoluble particles are removed from the resulting hydrous hydrolysis reaction mixture, thereby obtaining an aqueous solution containing a hydrophobic / hydrophilic polymer / low molecular peptide and a water-soluble amino acid, from which the hydrophobic resin column method is obtained. From the composition consisting of final purification by further loading the permeated fraction obtained by the above to ultrafiltration (molecular weight 1000) and permeation, or from the serine-tryptophan sequence That the dipeptide asparagine - dipeptide consisting of the sequence of tryptophan, glutamine - dipeptide consisting of SEQ tryptophan, glycine - dipeptides and alanine consisting of the sequence of the tryptophan - dipeptide consisting of SEQ tryptophan. [Selection figure] None |
| priorityDate | 2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.