| abstract |
Disclosed is an N-phenyl-N'-phenylsulfonylpiperazine derivative. Also disclosed is a method for efficiently producing an intermediate for the N-phenyl-N'-phenylsulfonylpiperazine derivative. Specifically disclosed is a method for producing a compound represented by the formula (III) below, which is characterized in that a compound represented by the formula (I) below is reacted with a compound represented by the formula (II) below in a solvent in the presence of a palladium compound, an organophosphorus compound and a base. (In the formula (I), R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP> and R<SUP>5</SUP> independently represent a hydrogen atom, a halogen atom, an optionally substituted alkyl, an optionally substituted alkyloxy or the like.) (In the formula (II), R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>9</SUP> and R<SUP>10</SUP> independently represent a hydrogen atom, a halogen atom, a hydroxy, an optionally substituted heteroaryl or the like; and X represents a halogen atom or the like.) (In the formula (III), R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP> R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>9</SUP> and R<SUP>10</SUP> are as defined above.) |