abstract |
The present invention provides a method represented by Scheme 1: nwherein nX nrepresents I, Br, Cl, alkylsulfonate, or arylsulfonate; nZ nrepresents optionally substituted aryl, heteroaryl or alkenyl; ncatalyst ncomprises a copper atom or ion, and a ligand; nbase nrepresents a Bronsted base; and nR nrepresents optionally substituted alkyl, cycloalkyl, aralkyl, heteroaralkyl, alkenylalkyl, or alkynylalkyl. |