http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4263094-B2
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 |
| filingDate | 2002-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-4263094-B2 |
| titleOfInvention | Glycine-substituted thieno [2,3-d] pyrimidine having LH and FSH combined agonist activity |
| abstract | The present invention resides in glycine substituted thieno[2,3-d]pyrimidine derivatives according to general formula I, or a pharmaceutically acceptable salt thereof, wherein X is O or H,H A is S, NH, N(R<SUP>6</SUP>), O or a bond; R<SUP>1 </SUP>is (1-4C)alkyl, (2-4C)alkenyl, phenyl or (2-5C)heteroaryl, the phenyl or heteroaryl ring optionally being substituted with one or more of the group of substituents: hydroxy, halogen, nitro, trifluoromethyl, cyano, amino or (1-4C)(di)alkylamino and R<SUP>2 </SUP>is H, (1-4C)alkyl, (1-4C)alkoxy(2-4C)alkyl or hydroxy(2-4C)alkyl; R<SUP>3 </SUP>and R<SUP>4 </SUP>can be independently selected from H and hydroxy(1-4C)alkyl; R<SUP>5 </SUP>is H or (1-4C)alkyl; R<SUP>6 </SUP>can be selected from the same groups as described for R<SUP>1</SUP>. The compounds of the invention have LH as well as FSH receptor activating activity and can be used in fertility regulating therapies. |
| priorityDate | 2001-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.