| abstract |
PROBLEM TO BE SOLVED: To provide an IGF-1R inhibitor containing an indazole derivative or a pharmacologically acceptable salt thereof as an active ingredient. [Means for Solving the Problems] Formula (I) Embedded image {Wherein R 1 represents —NR 4 R 5 [wherein R 4 represents a hydrogen atom, R 5 represents a substituted or unsubstituted lower alkyl, —C (═O) R 6 (where R 6 Represents a substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, etc.)] R 2 and R 3 are the same or different and each represents a hydrogen atom, hydroxy, substituted or unsubstituted lower alkoxy or the like, and an indazole derivative represented by the formula I or a pharmacologically acceptable salt thereof as an active ingredient Insulin-like growth factor receptor (IGF-1R) inhibitors and the like are provided. [Selection figure] None |