abstract |
[PROBLEMS] To provide a method for easily and reproducibly producing induced pluripotent stem cells having the same pluripotency and proliferation ability as ES cells by inducing the initialization of differentiated cells without using embryos or ES cells. To do. A method for producing induced pluripotent stem cells from somatic cells, the method comprising introducing the following four genes: Oct3 / 4, Klf4, c-Myc, and Sox2 into somatic cells. [Selection figure] None |