| abstract |
The present invention is a leukotriene biosynthesis inhibitor, Formula (Ia): [Wherein, X is O or S, Y is O, S—NR 6 —CHR 7 or —NR 8 —C (O) —, A is a 5-membered aromatic heterocycle, 6-membered aromatic heterocycle] Selected from rings, naphthalene or heterobicyclic aromatic ring systems, phenyl and benzyl. ] The compound of this is provided. A is optionally mono- or di-substituted. The compounds of formula (Ia) are useful as therapeutic agents for atherosclerosis, therapeutic agents for asthma, therapeutic agents for allergies, anti-inflammatory agents and cytoprotective agents. |