| abstract |
NEW MATERIAL:A compound expressed by formula I {X is formula II [R<2> is H, OH, alkyl, (substituted) aryl, etc.], etc.; Y is O or S; R<1> is H, alkyl, (substituted) aryl, etc.; R<3> is alkyl, cycloalkyl, alkenyl, etc.; R<4> and R<5> are H, lower alkyl, trifluoromethyl, halogen, lower alkanoyl, aroyl, etc.}. EXAMPLE:5-n-Butyl-1-methyl-1H, 5H-imidazo[4,5-c]quinoline-4-one. USE:A bronchodilator and antiallergic agent. PREPARATION:A compound expressed by formula III is reacted with a com pound expressed by the formula R<3>-Z (Z is eliminating group), preferably in the presence of a base (e.g. potassium carbonate or sodium methoxide) to pro vide the compound expressed by formula I (group X is formula II). |