abstract |
The present invention relates, in part, to fused heteroaryl compounds useful for preventing and/or treating diseases or conditions associated with abnormal functioning of voltage-gated sodium ion channels, e.g., abnormal protracted/protracted sodium currents. of composition or dosage form comprising Neurological disorders (e.g., Dravet syndrome, epilepsy), pain, neuromuscular disorders, trigeminal-autonomic headache (TAC), migraine, cranial neuropathy or polyneuropathy, and cortical spreading depression (CSD) Also provided herein are methods of treating diseases or conditions associated with abnormal function of sodium ion channels, including: In another aspect, the invention provides a method of making an ion channel modulator. |