| abstract |
The present disclosure relates to stable aqueous solutions containing high concentrations of anti-C5 antibodies (eg, ULTOMIRIS) and methods for preparing the solutions. The present disclosure uses solutions to treat or prevent complement-related disorders such as paroxysmal nocturnal hemoglobinuria (PNH) and thrombotic microangiopathy (TMA), including atypical hemolytic uremic syndrome (aHUS). It also provides a method for A further feature is a therapeutic kit containing one or more of the solutions. |