abstract |
Disclosed are aminotriazole compounds of formula (I). These compounds are inhibitors of acid mammalian chitinase and chitotriosidase. Also disclosed is the use of the compounds to treat asthmatic reactions induced by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurological diseases, metabolic diseases, liver diseases, polycystic ovary syndrome. , endometriosis, and cancer. [Chemical 1] [Selection figure] None |