| abstract |
The present disclosure is a method for preparing a compound of formula I, wherein the compound of formula II is reacted with an aqueous acid in a solvent at a sufficient temperature for at least about 48 hours to produce the compound of formula I. Step: [In the formula, R 1 to R 5 are as defined herein]. Provide methods, including. Also provided are compositions containing D-Metirosine prepared according to the methods described herein and D-Metirosine provided herein. |