| abstract |
Humanized anti-Aβ monoclonal antibodies and their use are provided. The provided humanized anti-Aβ monoclonal antibody inhibits the polymerization of Aβ monomer, protects nerve cells from the toxicity of Aβ, and has a certain effect on the improvement of cognitive learning and memory ability in Alzheimer's disease model mice. It can be used for the treatment and diagnosis of diseases and disorders associated with amyloidosis such as Alzheimer's disease. [Selection diagram] None |