abstract |
The present invention relates to drug delivery systems and methods of using delivery systems, in particular to delivery systems for transporting pharmaceutically active agents across, for example, the skin, the surface of the eye or the mucous membranes. The drug delivery system comprises a pharmaceutically effective moiety and a polyamine or amine moiety, the polyamine or amine moiety being characterized by the absence of two or more contiguous basic amino acid residues. The drug delivery system of the present invention may be provided for use as a pharmaceutical product or for the treatment of a disease or condition selected from eye diseases, burns, infections, and trauma. The invention also provides a method comprising administering a pharmaceutically effective amount of a drug delivery system of the invention to a patient in need thereof. |