| abstract |
The present invention comprises at least one container, a fluid medium contained in the container, producer cells, a liquid medium stirrer, and means for controlling the rate of stirrer suitable for the growth of the producer cells. A fluid system for loading therapeutic or contrast agents into the lumen of extracellular vesicles (EVs) from, also providing means for controlling the velocity of the stirrer, the shape and dimensions of the stirrer and container. Turbulence is applied to the liquid medium in the container to apply shear stress to the producer cells in order to carry out loading of the therapeutic agent or contrast agent into the lumen of extracellular vesicles (EV) simultaneously produced by the fluid system. With respect to a fluid system characterized by being suitable for. [Selection diagram] Fig. 1 |