| abstract |
The present invention provides amides that inhibit cellular necrosis and / or receptor interaction protein 1 (RIP1), corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. To. The compound of the present invention is used in a pharmaceutical composition, a method for producing a pharmaceutical, and a method for using the pharmaceutical, in which an effective amount of the compound or the composition is administered to a human in need of treatment. And to confirm the improvement by administration in the health or condition of the person. |