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filingDate 2019-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2022515549-A
titleOfInvention Pantothenamide analog
abstract The present invention provides compounds having antimalarial activity. More specifically, the present invention provides novel compounds that are analogs of pantothenamide. The pantotenamide analogs of the present invention have particularly low IC50 values for the asexual blood stage of Plasmodium malaria and germline mother cells. Also, the pantothenamide analogs of the present invention are characterized by low hepatic metabolism. Therefore, the pantotenamide analogs of the present invention are particularly suitable for use in the therapeutic and / or prophylactic treatment of protozoan infections in human or animal subjects in need thereof. The present invention further provides therapeutic and / or prophylactic use of pharmaceutical formulations containing pantotenamide analogs, as well as pharmaceutical formulations containing pantotenamide analogs and pantotenamide analogs.
priorityDate 2018-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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