abstract |
The present invention has the formula (I) capable of regulating the activity of CFTR. [Chemical 1] (In the formula, all variables are as defined herein) with respect to the heterocyclic compound. The present invention further provides a method for producing the compounds of the present invention, and therapeutic uses thereof. The present invention further provides methods of their preparation, their medical use, in particular their use in the treatment and management of diseases or disorders, including cystic fibrosis and related diseases. |