abstract |
The present invention belongs to the field of nucleic acid editing, and in particular to the technical field of clustered regularly spaced short chain palindromic repeats (CRISPR). Specifically, the present invention provides Cas effector proteins, fusion proteins of such proteins and nucleic acid molecules encoding them, and for nucleic acid editing (eg, gene or genome editing) comprising said protein or nucleic acid molecule. The complex and composition of the above, as well as methods for nucleic acid editing (eg, gene or genome editing) comprising said proteins. [Selection diagram] Fig. 1 |