abstract |
PROBLEM TO BE SOLVED: To provide a preparation for use in distributing an RNAi molecule targeting human GST-π for treating a malignant tumor in a subject. A pharmaceutical product can include nanoparticles composed of an ionizable lipid, a DSPE lipid, and an additional lipid. The product can be produced by freeze-drying the product. The present invention further provides a method for ameliorating or treating a malignant tumor by administering a therapeutically effective amount of a preparation containing an RNAi agent. [Selection diagram] Fig. 1 |