| abstract |
The embodiments of the present disclosure relate, as a whole, to a formulation, method, kit, and dosage form for an improved topical pharmaceutical formulation comprising an active ingredient, wherein the active ingredient is the formula (I). Includes a compound selected from the group consisting of formula (II) and formula (III): the formulation further comprises a hydrophilic nonionic surfactant containing poloxamer. These formulations are useful for treating inflammation, pruritus and / or pain by topical administration to a subject, or for treating conditions in which signs and symptoms include inflammation, pruritus and / or pain. |