abstract |
An antibody construct comprising a 4-1BB binding domain and an antigen binding domain that binds to a tumor-related antigen (TAA), wherein the 4-1BB binding domain and the TAA antigen binding domain are directly or indirectly linked to the scaffold. , Antigen constructs are described herein. The scaffold may be an Fc construct with modifications that reduce its ability to mediate effector function. TIFF2022504826000149.tif193128 |