| abstract |
Described is a cinnoline compound of formula (I), a variant thereof, and its use as an inhibitor of HPK1 (hematopoietic kinase 1). The compounds are useful in the treatment of HPK1-dependent disorders and in enhancing the immune response. Also described are methods of inhibiting HPK1, treating HPK1-dependent disorders, enhancing immune responses, and preparing cinnoline compounds. [Selection diagram] None |