| abstract |
Condensed compounds of formulas (I) and (II), pharmaceutical compositions containing them, methods of making them, and methods of using them include pain, psychiatric disorders, neurological disorders (major depressive disorders, treatment resistance). Includes methods for treating disease states, disorders and conditions associated with MGL regulation, such as, but not limited to, sexual depression, anxiety depression, bipolar disorder), cancer and those associated with eye conditions. [Chemical 1] In the formula, R 1 , R 2 , R 2a , R 3 , R 3a , R 4 and R 4a are defined herein. |