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filingDate 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2022157473-A
titleOfInvention A method for determining the presence or absence of a genetic predisposition to exhibit high serum uric acid levels after menopause, a method for detecting a single nucleotide polymorphism (SNP) allele, a composition, and a kit
abstract An object of the present invention is to provide a method for knowing the risk of developing hyperuricemia in adult women. A method for determining the presence or absence of a genetic predisposition to exhibit high serum uric acid levels after menopause, the method comprising the steps of: Genetic predisposition to exhibit high postmenopausal serum uric acid levels in an adult female subject when at least one of the following single nucleotide polymorphisms (SNPs) (a) to (c) in a nucleic acid derived from the subject is a risk allele: and determining that there is no genetic predisposition to exhibit a high serum uric acid level after menopause when none of the single nucleotide polymorphisms (SNPs) is a risk allele, The above-mentioned risk alleles are homozygous alleles that show a higher average serum uric acid level than the other homozygous type when comparing the average serum uric acid levels in populations having each of the two homozygous types. and The method, wherein the elevated serum uric acid level and the elevated serum uric acid level are a serum uric acid level of 7 mg/dL or more. (a) rs1351879 on human chromosome 2 (b) rs4430896 on human chromosome 2 (c) rs117377116 on human chromosome 12 [Selection figure] None
priorityDate 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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