| abstract |
An object of the present invention is to provide an edoxaban-containing pharmaceutical composition having excellent solubility of edoxaban in the neutral region. The pharmaceutical composition comprises (A) edoxaban, a pharmaceutically acceptable salt (eg, tosylate), or solvate (eg, hydrate) thereof, and (B) a water-soluble binder. Contains granules and does not contain organic acids. The granules are granules obtained by wet granulation using the dispersion of (A) and (B). [Selection figure] None |