http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022069256-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed3e9feb22b82bc70604d34288cbb954 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_069d9455be4dab110478bc83c502a3da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b042342adaa21df71edf47fe9fc3463f |
publicationDate | 2022-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2022069256-A |
titleOfInvention | New method for producing dabigatran etexilate methanesulfonate |
abstract | PROBLEM TO BE SOLVED: To provide a production method for efficiently preparing crystal form I of dabigatran etexilate methanesulfonate having a monomodal particle size distribution shape. SOLUTION: Crystal form I of dabigatran ethanelate methanesulfonate (davigatlan etexate methanesulfonate) is added as a seed crystal to a solution of dabigatran ethanelate base (free base) for 15 minutes to 48 hours. This is a production method for obtaining crystal form I of dabigatran etexilate methanesulfonate having a monomodal particle size distribution by adding methanesulfonic acid after stirring and stirring. [Selection diagram] Fig. 1 |
priorityDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.