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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
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filingDate 2021-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2022025104-A
titleOfInvention CNP prodrug with carrier binding in the ring moiety
abstract PROBLEM TO BE SOLVED: To provide a safer and more accessible type C natriuretic peptide (CNP) having a low risk of hypotension. SOLUTION: A carrier moiety-Z attached to a reversible prodrug linker moiety-L 1- via a CNP moiety-D including a ring moiety and a moiety-L 2- , wherein the reversible prodrug. The drug linker moiety -L 1- is covalently and reversibly bound to the side chain of the amino acid residue of the ring moiety of -D or to the skeleton of the ring moiety of -D. , Chemical bonds or spacers, CNP prodrugs or pharmaceutically acceptable salts of the prodrugs are used. [Selection diagram] Fig. 1
priorityDate 2016-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 44.