http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021534084-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-79 |
| filingDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021534084-A |
| titleOfInvention | Histone demethylase 5 inhibitor and its use |
| abstract | Compounds of formula (I) and formula (II), as well as pharmaceutically acceptable salts thereof, solvates, hydrates, polymorphs, cocrystals, tautomers, steric isomers, isotope-labeled derivatives, Prodrugs and compositions are provided herein. Proliferative disorders, cancers, cancers, lung cancers, breast cancers, liver cancers, pancreatic cancers, stomach cancers, ovarian cancers, colon cancers, colorectal cancers, leukemias, sarcomas and / or cardiovascular cancers in those who need it Also provided are methods and kits comprising the compounds or compositions disclosed herein for treating and / or preventing the disease. In certain embodiments, the sarcoma is Ewing's sarcoma. A method of inhibiting histone demethylase in a subject and / or a cell, tissue or biological sample is provided. In certain embodiments, the histone demethylase is KDM. In certain embodiments, the KDM is KDM5. In certain embodiments, the biological sample is a cell. In certain embodiments, the biological sample is tissue. [Chemical 1] [Selection diagram] FIG. 8 |
| priorityDate | 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.