abstract |
Isoquinoline compound of formula (I): The variants thereof, as well as their use as an inhibitor of HPK1 (hematopoietic precursor kinase 1) are described. The compounds are useful in the treatment of HPK1-dependent diseases and in enhancing the immune response. Also described are methods of inhibiting HPK1, treating HPK1-dependent diseases, enhancing immune responses, and preparing isoquinoline compounds. [Selection diagram] None |