http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021531340-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021531340-A |
| titleOfInvention | Inhibition of the PRC2 subunit to treat eye disorders |
| abstract | The present disclosure presents an inhibitor of one or more subunits of Polycomb Inhibition Complex 2 (PRC2) for use in the prevention or treatment of eye disorders in subjects in need thereof, and therapeutically effective amounts of polycomb. It provides a method of treating an eye disorder, eg, a non-cancerous disorder, in a subject using one or more inhibitors of the subunit of inhibitory complex 2 (PRC2). In certain embodiments of the methods of the present disclosure, ocular disorders are characterized by degeneration or cell death of retinal neurons. In certain embodiments of the methods of the present disclosure, the subunit of PRC2 is EZH1 or EZH2 and the inhibitor is an inhibitor of H3K27 trimethylation. |
| priorityDate | 2018-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 302.