| abstract |
The present disclosure describes chemical entities (compounds or pharmaceutically acceptable salts and / or hydrates and / or co-crystals and / or of the compounds) that inhibit (eg, antagonize) STING (Stimulator of Interferon Gene). Combination drug). The chemical entity increases STING activation (eg, STING signaling) in the pathology and / or symptoms and / or progression of a condition, disease, or disorder (eg, cancer) in a subject (eg, human), eg. It is useful for treating the condition, disease, or disorder to which (eg, enhancement) contributes. The disclosure also features compositions containing the chemical entity, as well as methods of using and producing the chemical entity. |