| abstract |
PROBLEM TO BE SOLVED: To provide a compound or the like according to the general formula (I). The present invention is a compound according to the general formula (I) acting as an inhibitor of PqsR (currently the only known receptor for Pseudomonas quinolone signal (PQS)); one of the compounds of the present invention or Uses of said compounds, including pharmaceutical compositions comprising multiple; combinational preparations comprising at least one compound of the invention and at least one additional active pharmaceutical ingredient; and pharmaceutical use, eg, bacterial infections, especially Pseudomonas aeruginosa. For use in the treatment or prevention of bacteria or Burkeholderia infections. [Selection diagram] None |