http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021522277-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2021522277-A |
| titleOfInvention | A pharmaceutical composition for the prevention or treatment of degenerative brain diseases containing ibrutinib as an active ingredient. |
| abstract | The present invention relates to a pharmaceutical composition for the prevention or treatment of degenerative brain disease containing ibrutinib as an active ingredient, and the ibrutinib of the present invention suppresses the activity of microglia or astrocytes and activates microglia. Alternatively, it has the effect of suppressing the damage of activated astrocytes to nerve cells, has an excellent effect of suppressing the cell migration of microglia induced by LPS (Lipopolytherapy), reduces amyloid plaques, and inhibits tau protein phosphorylation. Not only does it have activity, but it also has the effect of improving memory and learning ability, so it can be used as a therapeutic agent that can prevent or treat degenerative brain diseases. [Selection diagram] FIG. 27 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023163187-A1 |
| priorityDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.