| abstract |
The present invention relates to quinolines and quinosalin compounds represented by Chemical Formula 1, or pharmaceutically acceptable salts, stereoisomers, prodrug molecules or deuterated compounds thereof. The compounds of the present invention are effective in inhibiting the action of AXL protein kinases and can inhibit the growth, migration and infiltration of various tumor cells. Furthermore, the quinoline and quinozalin compounds of the present invention have excellent metabolic stability, high antitumor activity in vivo, low toxic side effects, and to prevent overgrowth diseases such as tumors in humans and other mammals. Can be used to prepare the drug of. [Selection diagram] Fig. 1 |