abstract |
The present invention relates to a tetrahydroisoquinoline derivative, a method for producing the same, and an application thereof. Specifically, the present invention relates to the tetrahydroisoquinoline derivative, or a pharmaceutically acceptable salt, ester, steric isomer, tautomer, or polymorph thereof. The present invention further relates to methods for producing the compounds, intermediates, pharmaceutical compositions containing the compounds, and the treatment or prevention of thromboembolic disorders thereof, with respect to the solvates, isotope-labeled compounds, metabolites or prodrugs. Regarding the use in. |