| abstract |
The present invention provides 25-hydroxycholecalciferol monohydrate crystals, a method for producing the same, and a microemulsion using the same. In the X-ray powder diffraction pattern of the 25-hydroxycholecalciferol monohydrate crystal of the present invention, 2θ is 10.035 °, 11.623 °, 14.631 °, 15.504 °, 15.551 °, 16 .471 °, 17.198 °, 19.002 °, 19.628 °, 20.109 °, 21.886 °, 23.113 °, 23.661 °, 24.701 °, 25.220 °, 25 Characteristic peaks are shown at .440 ° and 28.527 °. The 25-hydroxycholecalciferol monohydrate crystal of the present invention can effectively enhance the stability of 25-hydroxycholecalciferol, which is advantageous for the production and storage of related pharmaceuticals, and 25-hydroxychole. It is even more helpful in effectively utilizing the biological properties of calcifediol. [Selection diagram] Fig. 1 |