| abstract |
Provided are prodrugs of (S)-or (R) -ketamine containing isotope-labeled ketamine, compositions and uses thereof. A pharmaceutical composition comprising an isotope-labeled ketamine, a compound having formula (Ia) or (Ib) as a prodrug of (S)-or (R) -ketamine, and a compound provided herein. , Used to treat or prevent CNS disease. More specifically, related illnesses include depression and pain. (Ia) (Ib) |