http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021508338-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
filingDate | 2018-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2021508338-A |
titleOfInvention | Crystal form of sesquiterpene derivative, its preparation method and application |
abstract | The present invention provides a crystal form of a sesquiterpene derivative, a method for preparing the same, and an application thereof. In the powder X-ray diffraction pattern of the crystal form A, the 2θ diffraction angles are 6.840 ± 0.2 and 9.390 ± 0. .2, 15.980 ± 0.2, 16.830 ± 0.2, 17.780 ± 0.2, 18.760 ± 0.2, 19.340 ± 0.2, 20.400 ± 0.2 , 21.910 ± 0.2, 23.280 ± 0.2, 25.520 ± 0.2, 26.680 ± 0.2, 27.490 ± 0.2, 32.110 ± 0.2, 32 It has characteristic diffraction peaks at positions corresponding to .300 ± 0.2, 37.980 ± 0.2 and 44.230 ± 0.2. The crystalline form A of the present invention has a high degree of crystallinity, almost no hygroscopicity, shows a more preferable elution kinetics, and has a bioavailability of 85.8%. [Selection diagram] Fig. 1 |
priorityDate | 2017-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.