| abstract |
The present disclosure relates to a 2'3'cyclic phosphonate dinucleotide of general formula (J), a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and a combination of the above substance with another pharmaceutical product or formulation. .. The present disclosure is also related to the use of the compounds in the treatment or prevention of diseases or conditions that can be regulated by STING protein regulation, such as cancer or viral, allergic, or inflammatory diseases. In addition, these substances can be used as adjuvants in vaccines. |